3D Electron Microscopy: Some Challenges Ahead in Pattern Recognition
Prof. José María Carazo, Universidad Autonoma de Madrid, Spain

Seminar • 04 December 2003 • EPFL, BM.2.135

Abstract
The standard methodology for 3D electron microscopy will be reviewed making a special emphasis in pointing a number of methodological bottlenecks that nowadays preclude attaining a resolution below 1 nm in a routine fashion. The challenges will be illustrated with experimental examples in the field of structural studies of replicative helicases.