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A Method for Assessing the Fidelity of Optical Diffraction Tomography Reconstruction Methods Using Structured Illumination

A.B. Ayoub, T.-a. Pham, J. Lim, M. Unser, D. Psaltis

Optics Communications, vol. 454, no. 124486, pp. 1-6, January 1, 2020.



A fundamental challenge in 3D tomographic reconstruction is the difficulty of obtaining ground truth about test objects with which to assess the fidelity of the 3D reconstruction. We present a method that provides such a quantitative metric of the accuracy of the three dimensional reconstruction for optical tomography. The method relies on spatial light modulation of the illumination beam through the sample and numerical back-propagation of the phase conjugated experimentally measured optical field through the 3D reconstruction of the object. The fidelity of this reconstruction provides a quantitative measure of the accuracy of the 3D reconstruction without direct access to the ground truth about the 3D object.


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AUTHOR="Ayoub, A.B. and Pham, T.-a. and Lim, J. and Unser, M. and
        Psaltis, D.",
TITLE="A Method for Assessing the Fidelity of Optical Diffraction
        Tomography Reconstruction Methods Using Structured Illumination",
JOURNAL="Optics Communications",
YEAR="2020",
volume="454",
number="124486",
pages="1--6",
month="January 1,",
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