Biomedical Imaging GroupSTI
English only   BIG > Publications > Ejection Fraction

 Home Page
 News & Events
 Tutorials and Reviews
 Download Algorithms

 All BibTeX References

Segmentation of Gated SPECT Images for Automatic Computation of Myocardial Volume and Ejection Fraction

P. Brigger, S.L. Bacharach, A. Aldroubi, M. Unser

Proceedings of the 1997 IEEE International Conference on Image Processing (ICIP'97), Santa Barbara CA, USA, October 26-29, 1997, vol. II, pp. 113-116.

We describe an image processing system for the automatic assessment of ejection fraction (EF) from noisy SPECT left ventricular myocardial perfusion images. A segmentation scheme consisting of an elliptical coordinate transformation, matched filtering and dynamic contour tracking detects the endo- and epi-cardial boundaries. Computation of EF is performed based on the epi- rather than the endo-cardial boundary, which proves to be more robust for images with low signal-to-noise ratios. The computation incorporates anatomical constraints of constant myocardial mass and smooth cardiac variation. The algorithm was tested on different image modalities and shows good linear agreement with EFs obtained from conventional approaches based on planar gated blood pool imaging (PET: y = 8.7 + 1.07 x, r = 0.84, Technetium-99m MIBI SPECT: y = 5.0 + 0.80 x, r = 0.90, Thallium-201 SPECT: y = 23.5 + 0.82 x, r = 0.77, RMS error = 10.0). The proposed scheme may be an alternative for EF computation without the need for additional image acquisitions.

AUTHOR="Brigger, P. and Bacharach, S.L. and Aldroubi, A. and
        Unser, M.",
TITLE="Segmentation of Gated {SPECT} Images for Automatic
        Computation of Myocardial Volume and Ejection Fraction",
BOOKTITLE="Proceedings of the 1997 {IEEE} International Conference
        on Image Processing ({ICIP'97})",
address="Santa Barbara CA, USA",
month="October 26-29,",

© 1997 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from IEEE.
This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.