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Accurate MR Cardiac Perfusion Analysis by Using a Multiresolution B-Splines Registration Algorithm

C. Dornier, M.K. Ivancevic, P. Thévenaz, M. Unser, J. Vallée

Proceedings of the Eleventh Scientific Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM'03), Toronto ON, Canada, July 10-16, 2003, pp. 700.



We acquire MR cardiac perfusion in free-breathing mode. Along the whole sequence, we observe large variations in the position of the left ventricle on short-axis views. We evaluate here an automatic and freely available registration algorithm for performing an accurate perfusion analysis. This algorithm automates the otherwise tedious and time-consuming shift of the different regions of interest, which is needed to reach sufficient accuracy in the perfusion analysis. We validate the accuracy of this algorithm by calculating the geometric residual displacements of the left ventricle and by fitting the data to a compartment model with 2 parameters.


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