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Time Resolved Fluorescence Diffuse Optical Tomography Using Multi-Resolution Exponential B-Splines

N. Ducros, A. Da Silva, J.-M. Dinten, C.S. Seelamantula, M. Unser, F. Peyrin

Proceedings of the Sixth IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI'09), Boston MA, USA, June 28-July 1, 2009, pp. 157-160.



This paper deals with the problem of time-resolved fluorescence diffuse optical tomography. We propose a new reconstruction scheme based on a multi-resolution approximation of the time-resolved signals. The underlying basis functions are exponential B-splines that are matched to the decay of fluorescence signals. We illustrate the applicability of the method on phantom data.


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