Measuring Ocular Blood Flow Using a Hessian Operator

Blaise Robert

Semester Project

Section Microtechnique, EPFL

June 2015

Abstract

The in vivo measure of the retinal blood flow is very important to diagnose ocular diseases. The blood velocity can be derived from laser Doppler velocimetry. The goal of this project was to develop a method to measure the local diameter of the vessels in order to be able to estimate the retinal blood flow. The method that was developed is based on a Hessian operator. The method was implemented in Matlab and was tested on both synthetic and real images. The only parameter that the user has to set is the location on the image where he wants to perform the measurement. We were able to successfully estimate the diameters of ocular vessel with an error independent on the orientation of the vessel