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DeepImageJ: Bridging Deep Learning to ImageJ

E. Gomez-de-Mariscal, C. Garcia-Lopez-de-Haro, A. Munoz-Barrutia, D. Sage

European Light Microscopy Initiative 2021 (elmi'21), Virtual, June 22-25, 2021.


In the last decade, the use of Deep Learning (DL) methodologies has made a vast improvement in the solution of several bioimage analysis tasks such as denoising, super-resolution, segmentation, detection, tracking, response prediction, or computer-aided diagnosis [2]. These techniques support automatic image processing workflows and have demonstrated potential to surpass human-level performance in common tasks. Consequently, they have a profound impact on the way life-science researchers conduct their bioimage data analysis [1]. Nonetheless, the integration of this breakthrough technology into life-science research pipelines remains still a challenge for the scientific community. Training and evaluating DL models requires previous programming expertise and technical knowledge about Machine Learning. Therefore, the transfer of this technology to the daily practice of life sciences researchers remains a bottleneck. Aware of the latter situation, there are already some pioneer works that target the very need of making DL solutions accessible through user-friendly software [3, 4, 5, 6, 7]. Moreover, there is an increasing interest in the bioimage analysis community to teach and learn some general knowledge about DL and democratize it.

References

  1. E. Meijering, "A Bird's-Eye View of Deep Learning in Bioimage Analysis," Computational and Structural Biotechnology Journal, vol. 18, pp. 2312-2325, 2020.

  2. F. Xing, Y. Xie, H. Su, F. Liu, L. Yang, "Deep Learning in Microscopy Image Analysis: A Survey," IEEE Transactions on Neural Networks and Learning Systems, vol. 29, no. 10, pp. 4550-4568, October 2018.

  3. L. von Chamier, R.F. Laine, R. Henriques, "Artificial Intelligence for Microscopy: What You Should Know," Biochemical Society Transactions, vol. 47, no. 4, pp. 1029-1040, July 31, 2019.

  4. M. Weigert, U. Schmidt, T. Boothe, A.M&#;252ller, A. Dibrov, A. Jain, B. Wilhelm, D. Schmidt, C. Broaddus, S. Culley, M. Rocha-Martins, F. Segovia-Miranda, C. Norden, R. Henriques, M. Zerial, M. Solimena, J. Rink, P. Tomancak, L. Royer, F. Jug, E.W. Myers, "Content-Aware Image Restoration: Pushing the Limits of Fluorescence Microscopy," Nature Methods, vol. 15, no. 12, pp. 1090-1097, December 2018.

  5. U. Schmidt, M. Weigert, C. Broaddus, G. Myers, "Cell Detection with Star-Convex Polygons," Proceedings of the Twenty-First International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI'18), Granada, Kingdom of Spain, September 16-20, 2018, [Lecture Notes in Computer Science, vol. 11071, Springer, 2018], pp. 265-273.

  6. C. Stringer, T. Wang, M. Michaelos, M. Pachitariu, "Cellpose: A Generalist Algorithm for Cellular Segmentation," Nature Methods, vol. 18, no. 1, pp. 100-106, January 2021.

  7. W. Ouyang, F. Mueller, M. Hjelmare, E. Lundberg, C. Zimmer, "ImJoy: An Open-Source Computational Platform for the Deep Learning Era," Nature Methods, vol. 16, no. 12, pp. 1199-1200, December 2019.

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