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Assessment of Chromosomal Length Variation in CHO Cells

P.O. Michel, R. Delgado-Gonzalo, M. Hubert, L. Baldi, D.L. Hacker, M. Unser, F.M. Wurm

Proceedings of the Twenty-Third Meeting of the European Society for Animal Cell Technology (ESACT'13), Lille, French Republic, June 23-26, 2013, pp. 206.


Chinese hamster ovary (CHO)-derived cells are widely used for the production of recombinant proteins. Currently, the pharmaceutical industry relies on stable cell clones for therapeutic protein production. Most of the currently used methods to analyze clonality and stability in recombinant cell lines only take into consideration the cellular phenotype. However, few rapid methods are available to study clonality and genomic stability in recombinant cell populations.

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AUTHOR="Michel, P.O. and Delgado-Gonzalo, R. and Hubert, M. and Baldi,
	L. and Hacker, D.L. and Unser, M. and Wurm, F.M.",
TITLE="Assessment of Chromosomal Length Variation in {CHO} Cells",
BOOKTITLE="Proceedings of the Twenty-Third Meeting of the European
	Society for Animal Cell Technology ({ESACT'13})",
YEAR="2013",
editor="",
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pages="206",
address="Lille, French Republic",
month="June 23-26,",
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© 2013 ESACT. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from ESACT. This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.
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