BIOMEDICAL IMAGING GROUP (BIG)
Laboratoire d'imagerie biomédicale (LIB)

Optimal-Transport-Based Metric for SMLM

Q. Denoyelle, T.-a. Pham, P. del Aguila Pla, D. Sage, M. Unser

Proceedings of the Eighteenth IEEE International Symposium on Biomedical Imaging (ISBI'21), Nice, French Republic, April 13-16, 2021, pp. 797–801.

We propose the use of Flat Metric to assess the performance of reconstruction methods for single-molecule localization microscopy (SMLM) in scenarios where the ground-truth is available. Flat Metric is intimately related to the concept of optimal transport between measures of different mass, providing solid mathematical foundations for SMLM evaluation and integrating both localization and detection performance. In this paper, we provide the foundations of Flat Metric and validate this measure by applying it to controlled synthetic examples and to data from the SMLM 2016 Challenge. 

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AUTHOR="Denoyelle, Q. and Pham, T.-a. and del Aguila Pla, P. and Sage,
	D. and Unser, M.",
TITLE="Optimal-Transport-Based Metric for {SMLM}",
BOOKTITLE="Proceedings of the Eighteenth IEEE International Symposium on
	Biomedical Imaging ({ISBI'21})",
YEAR="2021",
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pages="797--801",
address="Nice, French Republic",
month="April 13-16,",
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