Compensation of lipids signal in in-vivo MRSI using B-SLIM
2008
Master Diploma
Project: 00174
Magnetic resonance spectroscopic imaging (MRSI) is an important technique for in both research in neurology and clinical practice. Unfortunately, the slow acquisition time limits the attainable spatial resolution. Typically, the spectroscopic image is limited to 16x16 only. An important consequence is the leakage of the strong signal due to lipids present in the brain's skull, into the intra-brain regions, making the evaluation of metabolite signals difficult or even impossible.
Recently, we proposed a new technique called B-SLIM (Spectral Localization by Imaging with B0 field compensation). The aim of this work is to apply our technique to in-vivo data in order to cancel out the undesired lipid signal.
This project is in collaboration with the "Center for Biomedical Imaging" (CIBM). The student will actively assist to an MRSI acquisition in the University Hospital of Geneva (HUG).
- Supervisors
- Dimitri Van De Ville, dimitri.vandeville@epfl.ch, 021 693 51 42, BM 4.140
- Michael Unser, michael.unser@epfl.ch, 021 693 51 75, BM 4.136
- Ildar Khalidov