We are interested in understanding the mechanisms governing asymmetric cell division, a process crucial for the development of multicellular organisms and for stem cell lineages. In this project, using available 3D image sequences, you will develop and apply image analysis methods to monitor in a quantitative manner the behavior of GFP-tagged components at the plasma membrane of asymmetrically dividing C. elegans one-cell stage embryos. The project consist to design algorithms to detect the membrane in 3D image and to segment the cells only based one the membrane. the implementation will be in Java as an ImageJ or Icy plugin.