EPFL
 Biomedical Imaging GroupSTI
EPFL
  Publications
English only   BIG > Publications > Chromosome Analysis


 CONTENTS
 Home Page
 News & Events
 People
 Publications
 Tutorials and Reviews
 Research
 Demos
 Download Algorithms

 DOWNLOAD
 PDF
 Postscript
 All BibTeX References

User-Friendly Image-Based Segmentation and Analysis of Chromosomes

V. Uhlmann, R. Delgado-Gonzalo, M. Unser, P.O. Michel, L. Baldi, F.M. Wurm

Proceedings of the Thirteenth IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI'16), Prague, Czech Republic, April 13-16, 2016, pp. 395-398.



We designed two efficient and user-friendly tools for the segmentation and analysis of images containing chromosomes or, more generally, rod-shaped elements that are spread on microscopic slides. The segmentation tool allows to automatically extract the profile of each chromosome and to sort the collection of profiles in a karyotype image. The analysis tool is interactive and allows to extract quantitative measurements and annotate the relative position of the centromere to the chromosome extremities in a fast and reproducible way. The two methods rely on custom variants of parametric active contours. Both have been designed as user-friendly plug-ins for the open-source software ImageJ.


@INPROCEEDINGS(http://bigwww.epfl.ch/publications/uhlmann1603.html,
AUTHOR="Uhlmann, V. and Delgado-Gonzalo, R. and Unser, M. and Michel,
        P.O. and Baldi, L. and Wurm, F.M.",
TITLE="User-Friendly Image-Based Segmentation and Analysis of
        Chromosomes",
BOOKTITLE="Proceedings of the Thirteenth {IEEE} International Symposium
        on Biomedical Imaging: {F}rom Nano to Macro ({ISBI'16})",
YEAR="2016",
editor="",
volume="",
series="",
pages="395--398",
address="Prague, Czech Republic",
month="April 13-16,",
organization="",
publisher="",
note="")

© 2016 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from IEEE.
This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.